The Breakthrough Drug That Took Me from Stage 4 to Cancer-Free


lung cancer


When Lalisha was diagnosed with stage IV small cell lung cancer (SCLC), doctors didn’t offer much hope. The cancer was aggressive. The odds were grim. And yet — she’s here. Alive. In remission. And advocating for others to fight just as hard as she did.


Her story is one of pain, persistence, and one bold decision that changed everything: to seek better answers and push for a treatment no one had offered her before.


That treatment, tarlatamab, was just spotlighted at the 2025 ASCO Annual Meeting. It wasn’t a guarantee. But for Lalisha, it worked. Just months later, a scan showed no evidence of cancer in her body.


Here’s how she got there — and the advice she’s sharing with anyone facing the same fight.


In October 2023, Lalisha was diagnosed with stage IV small cell lung cancer. The news hit hard. “I went so quickly from limited-stage to extensive-stage,” she tells BlackDoctor.org. “The first thing that went through my mind was, how am I going to survive this?”


Small cell lung cancer is aggressive and fast-spreading. Lalisha’s cancer continued to advance even after multiple rounds of chemotherapy. The physical toll was intense: bone pain, fatigue, weakness that made it difficult to even get out of bed or dress herself. Emotionally, she was navigating depression, grief, and the terrifying task of coming to terms with her mortality.


But she didn’t stop fighting.


A Critical Turning Point


When treatment at her initial care facility wasn’t delivering the clarity or results she needed, Lalisha took matters into her own hands. Her decision to drive herself to the Mayo Clinic was rooted in a deep mistrust born of personal history — her mother had died at 39 due to inadequate healthcare. On top of that, unclear and inconsistent communication from her physician pushed her to seek a second opinion.


At the Mayo Clinic, she found a team that acted fast. “The first thing they told me was that surgery had to be done quickly,” she said. After surgery, her oncologist introduced her to a new treatment option: tarlatamab, a promising drug developed by Amgen. 


A Breakthrough Treatment


Lalisha’s cancer had invaded her entire body. Her care team moved fast. Even before the next scan was complete, arrangements were being made behind the scenes to get her access to tarlatamab. She was hospitalized for her first two doses, experiencing side effects like cytokine release syndrome (CRS), but by the third dose, something changed.


She started to feel better.


Two months later, a PET scan revealed a stunning result: no evidence of active cancer.


“It was the best news I’ve ever received,” Lalisha says. “My mental health improved. My physical health improved. I could walk without fear of falling. I could play basketball again. I had my life back.”


From Survivor to Advocate


Lalisha didn’t stop at survival. A retired social worker with 30 years of experience, she found renewed purpose in helping others navigate their own battles with cancer. She now facilitates a support group for small cell lung cancer survivors, speaks at conferences, and answers questions from others weighing their treatment options.


“I look at myself as an example of what happens when researchers, medical providers, and scientists focus on truly helping patients live,” she says.


Calling for Systemic Change


Her story is also a call to action, especially for healthcare providers. “Some doctors become pessimistic and say things like, ‘This is going to take you out.’ That kind of language kills hope. We need providers who treat us like survivors, not statistics,” she adds.


Lalisha wants to see better access to lifesaving medications like tarlatamab, especially in small or under-resourced hospitals, and for patients of color who often face disparities in care. Her journey underscores the power of second opinions, patient self-advocacy, and equitable access to innovation.


Hope for the Future


Today, Lalisha wakes up with joy and gratitude. “There will be storms in my life,” she says, “but I’ve learned how to dance in the morning.”


She continues to advocate for a future where no one with small cell lung cancer feels overlooked or defeated — where treatment isn’t just about survival, but about reclaiming life.


Her message is simple, but powerful:


“You are the chief navigator of your care. Speak up. Ask questions. Get the second opinion. It’s your life — and you are in charge,” she concludes.


Tips for Those Facing Small Cell Lung Cancer


Whether you’re newly diagnosed or deep in treatment, here are some of Lalisha’s takeaways that may help:


1. Get a Second Opinion


If something doesn’t feel right, get another perspective. Your life is worth the extra effort.


2. Advocate Relentlessly


You are the leader of your care team. If a treatment plan doesn’t sit well with you, say something. Don’t stay silent.


3. Don’t Lose Hope


Even with aggressive cancers like small cell, progress is being made. New drugs like tarlatamab are emerging — stay informed and open to clinical trials or experimental options.


4. Build a Care Network


Surround yourself with people who will support and advocate with you: caregivers, family, friends, other patients, or support groups.


5. Address Mental Health


Grief, fear, and depression are real. Don’t go through it alone — talk to a counselor or palliative care team about emotional support.


6. Push for Equity


If you’re from a marginalized background, know that disparities in care exist, and push harder. Don’t let the system overlook you.


7. Celebrate Every Victory


Whether it’s walking down the hall or getting back on the basketball court, small wins are huge. Embrace joy where you can.